Dấu hiệu Pemberton

Mô tả: The development of facial flushing, neck distension, engorged neck veins, stridor and raised JVP when a patient raises and holds the arms above the head.

Nguyên nhân: • Retrosternalsubsternal goitre – common • Tumour

Cơ chế: When the arms are raised, the ring of the thoracic inlet is brought upwards and gets stuck on the goitre. The goitre is said to ‘cork’ the thoracic inlet and, in doing so, compresses the adjacent internal jugular veins. Blood backs up, causing distension of the neck veins and facial plethora. Stridor occurs with pressure on the upper airway from any mass, be it tumour or goitre.

Ý nghĩa lâm sàng: The frequency of Pemberton’s sign is unknown in patients with substernal goitres.23