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1          Ameriacan Diabetes Association (2005), "Defining and Reporting Hypoglycemia in Diabetes: a report from the Ameriacan Diabetes Association Workgroup on Hypoglycemia". Diabetes Care, 28(5), pp. 1245-1249. 2          American Diabetes Association (ADA) Diabetes Guidelines (2016 ), Summary Recommendations from NDEI. 3          Arniel S.A. et al (1993), "Gender differences in counterregulation to hypoglycaemia". Diabetologia   36, pp. 46-64. 4          Asian - Pacific Type 2 Diabetes Policy Group (2005), Type 2 Diebetes: Practical Targets and Treaments, 4th Edition, pp. 1-58. 5          Ben-Ami H et al (1999), "Glibenclamid - induced hypoglycaemia coma in 51 older patients with type 2 diabetes mellitus". JAGS, 47, pp. 631-633. 6          Bonds DE, Miller ME, Bergenstal RM, et al (2010), "The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemio-logical analysis of the ACCORD study". BMJ, 340, pp. b4909. 7          Briscoe V.J., Davis S.N. (2006), "Hypoglycemia in Type 1 and Type 2 Diabetes : Physiology, Pathophysiology, and Managerment". Clin Diabetes, 24, pp. 115-121. 8          Cryer P.E. (2007), "Hypoglycemia, functional brain failure, and brain death". J Clin Invest, 117(4), pp. 868-870. 9          Cryer P.E., Davis S.N. (2003), "Hypoglycemia in diabetes". Diabetes Care, 26(6), pp. 1902-1912. 10        Desouza C, Salazar H, Cheong B, Murgo J, Fonseca V (2003), " Association  of hypoglycemia and cardiac ischemia: a study based on continuous  monitoring". Diabetes Care, 26, pp. 1485-1489. 11        Diabetes Control and Complications Trial Research Group (1993), "The effect of intensive treatment of diebetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus". New England Journal of Medicine, 329(14), pp. 977-986. 12        Diabetes Control and Complications Trial Research Group (2007), "Long-term effect of diabetes and its treatment on cognitive function". The New England journal of medicine, 356(18), 1842-1852. 13        Duckworth W, Abraira C, Moritz T, et al (2009), "VADT Investigators. Glucose control and vascular complications in veterans with type 2 diabetes". N Engl J Med, 360, pp. 129-139. 14        Gerstein HC, Miller ME, Byington RP, et al (2008), "Action to Control Cardiovascular Risk in Diabetes Study Group. Effects of intensive glucose lowering in type 2 di- abetes". N Engl J  Med 358, pp. 2545-2559. 15        Ginde AA et al (2008), "Trends and Disparities in U.S. Emergency Department Visits for Hypoglycemia, 1993-2005". Diabetes Care, 31, pp. 511-513. 16        Green AJ, Fox KM Grandy S (2012), "Self-reported hypoglycemia and  impact on  quality of life and  depression among adults with type 2 diabetes mellitus". SHIELD Study Group. Diabetes Res Clin Pract, 96, pp. 313-318. 17        Harrison's Principles of Internal Medicine (2012), Hypoglycemia, 18th Edition, vol 1, part 16, section 1, chapter 345. 18        Henderson J.N. et al (2003), "Hypoglycaemia in insulin-treated Type 2 diabetes: frequency, symptoms and impaired awareness". Diabetes Med, 29, pp. 1016-1021. 19        Holstein A et al (2001), "Lower incidence of severe hypoglycaemia in patients with type 2 diabetes treated with glimepirid versus glibenclamid". Diabetes Metab Res Rev 17, pp. 467-473. 20        Holstein A., Egberts E.H. (2003), "Risk of Hypoglycemia with Oral Antidiebetes Agents in Patients with Type 2 Diebetes". Experimental and Clinical Endocrinology & Diabetes, 111, pp. 405-414. 21        Johnston SS, Conner C, Aagren M, Ruiz K, Bouchard J (2012), "Association between hypo- glycaemic events and fall-related fractures in Medicare-covered patients with type 2 diabetes". Diabetes Obes Metab, 14, pp. 634-643. 22        Johnston SS, Conner C, Aagren M, Smith DM, Bouchard J, Brett J (2011), "Evidence linking hypoglycemic events to an increased risk of acute cardiovascular events in patients with type 2 diabetes". Diabetes Care, 34, pp. 1164-1170. 23        Kahn C.R., Weir G.C., et al (2005), Joslin’s Diabetes Mellitus, 14th, Lippincott Williams & Wilkins, pp. 671-686. 24        Laiteerapong N, Karter AJ, Liu JY, et al (2011), "Correlates of quality of life in older adults with diabetes: the diabetes & aging study". Diabetes Care, 34, pp. 1749-1753. 25        Landstedt - Hallin L. et al (1999), "Increased QT dispersion during hypoglycaemia in patients with type 2 diabetes mellitus". J Intern Med, 246, pp. 299-307. 26        Lipska K.J., Warton EM, Huang ES, Moffet HH, Inzucchi SE, Krumholz HM, Karter AJ (2013 Jul 30 [Epub ahead of print]), "HbA1c and Risk of Severe Hypoglycemia in Type 2 Diabetes: The Diabetes and Aging Study". Diabetes Care. 27        McCoy RG, Van-Houten HK, Ziegenfuss JY, Shah ND, Wermers RA, Smith SA (2012), "Increased mortality of patients with diabetes reporting severe hypoglycemia". Diabetes Care 35 (9), pp. 1897-1901. 28        Miller C.D. et al (2001), "Hypoglycemia in Patients With Type 2 Diabetes Mellitus". Arch Intern Med, 161, pp. 1653-1659. 29        Miller ME, Bonds DE, Gerstein HC, et al ( 2010), "The  effects  of baseline characteristics, glycaemia treatment approach, and glycated haemoglo- bin concentration on the risk of  severe hypoglycaemia: post hoc epidemiological analysis of the ACCORD study". ACCORD Investigators. BMJ 340, pp. b5444. 30        Patel A, MacMahon S, Chalmers J, et al (2008), "ADVANCE Collaborative Group. In-tensive blood glucose control and vas-cular outcomes in patients with type 2 diabetes". N Engl J Med, 358, pp. 2560-2572. 31        Patel A, MacMahon SJ, J Chalmers et al (2008), "Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes". ADVANCE  Collaborative Group. N Engl J Med 358, pp. 2560-2572. 32        Schwartz AV, Vittinghoff E, Sellmeyer DE, et al (2008), "Health, Aging, and Body Compo- sition Study. Diabetes-related compli- cations, glycemic control, and falls  in older adults". Diabetes Care, 31, pp. 391- 396. 33        Seaquist ER, Anderson J, Childs B, Cryer P, Dagogo-Jack S, Fish L, Heller SR, Rodriguez H, Rosenzweig J, Vigersky R (2013 May [Epub 2013 Apr 15]), "Hypoglycemia and diabetes: a report of a workgroup of the American Diabetes Association and the Endocrine Society". Diabetes Care, 36 (5), pp 1384-1395. 34        Shorr RI et al (1997), "Individual sulfonylureas and seriuos hypoglycemia in older people". JAGS, 44, pp. 751-755. 35        UK Prospective Diabetes Study (UKPDS) Group (1998), " Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 di- abetes (UKPDS 33)". Lancet  352, pp. 837-853. 36        Whitmer RA, Karter AJ, Yaffe K, QuesenberryCP Jr, Selby JV ( 2009), "Hypoglycemic episodes and risk of dementia in older patients with  type  2  diabetes mellitus". JAMA, 301, pp. 1565-1572. 37        World Diabetes Foundation (2011), Diabetes Atlas., from http: www.worlddiabetesfoundation.org/composite-58,  on September 15th, 2013. 38        Zoungas S, Patel A, Chalmers J, et al (2010), "ADVANCE Collaborative Group. Severe hypoglycemia and risks of vascular events and death". N Engl J Med, 363, pp. 1410-1418.

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