The situation of the use of prophylactic antibiotics at Van Hanh General Hospital in 2022

Résumé

Introduction Surgical site infections (SSIs) remain a major concern in hospitals. However, prophylactic antibiotics have been proven effective in reducing infection risks. This study provides a comprehensive analysis of prophylactic antibiotic utilization at Van Hanh General Hospital in 2022. Materials and Methods A retrospective analysis was conducted using patient records and drug inventory data from January 1 to December 31, 2022. Descriptive statistics were applied to assess demographics, usage trends, and ABC cost analysis. Results A total of 388 medical records meeting the inclusion criteria were analyzed. The majority of patients were female (67.8%) with a median age of 32 years. All patients had an ASA score < 3 and NNIS score < 2. The median surgical duration was 80 minutes, and 62.9% of patients had a hospital stay of two days. Among the procedures, 66.2% were classified as clean surgeries, and 68.3% were open surgeries. Amikacin was the most frequently used antibiotic, accounting for 44.2% of cases. Prophylactic antibiotics were administered in 23.1% of cases before surgery and 76.5% during surgery. Antimicrobial agents were the most commonly used drug category (22.1%). Cefoperazone + Sulbactam, classified as a Tier A medication, accounted for only 2.1% of the total inventory. Conclusion The analysis highlights a significant proportion of antimicrobial agents in the hospital’s drug formulary, with three prophylactic antibiotics categorized as high- cost (Category A) drugs. To enhance antibiotic prophylaxis, strict monitoring, adherence to guidelines, and regular formulary reviews are essential for cost control and effective procurement planning. DOI: 10.59715/pntjmp.4.2.5