(Panel A) Total number of new publications listed in MEDLINE by year.
(Panel B) Number of publications of randomized trials listed in MEDLINE by year. Data were derived from searching Ovid MEDLINE® 1946 to February Week 4 2015 (searched on March 2, 2015) using the "Find Citation" tab for each year 1946 to 2013. The total number of citations was recorded. This was then limited to randomized controlled trials.