Oral progestin-only regimens

Suggested oral progestin/progesterone-only regimens for the acute management of anovulatory uterine bleeding and maintenance therapy after acute bleeding is controlled*

Preferred regimen for acute management
Norethindrone acetate	5 or 10 mg orally nightly^¶ until bleeding stops and anemia resolves
Preferred maintenance regimens^Δ
Oral micronized progesterone	200 mg orally nightly for the first 12 days of each calendar month (if not allergic to peanuts)^◊
Norethindrone acetate	5 mg orally nightly for the first 5 to 10 days^Δ of each calendar month^◊
Alternative maintenance regimen
Medroxyprogesterone acetate	10 mg orally nightly for the first 10 days of each calendar month^◊

* For patients who do not desire contraception.
¶ May be administered up to four times per day if acute bleeding is severe.
Δ We suggest taking oral progesterone on the first 5 to 12 days of each calendar month because it is easier for adolescents to remember than other regimens.
◊ Discontinue if menstrual bleeding occurs while taking oral progesterone.

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